In this talk, I will focus on what we can learn from large-scale sequestration in the USA.  Since 2020, 12 Class II and 5 Class VI wells have been permitted for CO2 sequestration in the USA.  Currently, 13 projects report against their M&V plans annually.  This body of experience gives a good idea of what practical M&V plans entail and shows that monitoring geological storage need not be elaborate or expensive.